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Marie Louise Landry, M.D.
Professor and Vice-Chair of Laboratory Medicine
Director, Virology Laboratory
Director, Medical Studies

(203) 688-3475
marie.landry@yale.edu

1970, B.A., University of Massachusetts, Amherst, MA
1974, M.D., Georgetown University School of Medicine, Washington, D.C.
Residency: Internal Medicine, Yale New Haven Hospital, 1974-1977
Fellowships: Infectious Diseases and Clinical Virology, 1978-1981; Departments of Internal Medicine and Laboratory Medicine, Yale University School of Medicine
Board certifications: Internal Medicine and Infectious Diseases

Community of Science Biosketch

Research Interests
My interests focus on the rapid detection and quantitation of viruses for clinical diagnosis and the impact of new test methods on patient management. Ongoing projects include optimization of rapid assays for respiratory viruses and herpesviruses and development of real-time molecular methods for viral diagnosis.

Selected References:

1. Landry, M.L. and Hsiung, G.D. Primary isolation of viruses. In Clinical Virology Manual, Specter SS, Hodinka R and Young S (Eds), 3 rd edition, American Society for Microbiology Press, Washington, D.C. 2000.
2. Landry ML, Stanat S, Biron K, et al. Standardized plaque reduction assay for determination of drug susceptibilities of cytomegalovirus clinical isolates. Antimicrob Agents Chemother 44:688-692, 2000.
3. Landry ML, Ferguson D. SimulFluor Respiratory Screen for rapid detection of multiple respiratory viruses in clinical specimens by immunofluorescence staining. J Clin Microbiol 38:708-711, 2000.
4. Landry ML, Ferguson D. Reduced ability to culture cytomegalovirus from peripheral blood leukocytes isolated by direct erythrocyte lysis. J Clin Microbiol 38:3906, 2000.
5. Stoner GL, Alappan, R, Jobes DV, Ryschkewitsch CF, and Landry ML. BK virus regulatory region rearrangements in brain and CSF from a leukemia patient with tubulointerstitial nephritis with meningoencephalitis Am J Kid Dis 39:1102-1112, 2002.
6. Landry ML, Garner R, Fergsuon D. Rapid enterovirus RNA detection in clinical specimens using nucleic acid sequence based amplification (NASBA). J Clin Microbiol 41:346-350, 2003.
7. Landry, ML, Ferguson D. Suboptimal detection of influenza in adults by Directigen Flu A + B and correlation with number of antigen-positive cells detected by cytospin immunofluorescence. J Clin Microbiol 41:3407-3409; 2003.
8. Habib-Bein NF , Beckwith WH, Mayo D, and Landry ML. SmartCycler Real-Time RT-PCR diagnosis of influenza A virus in a public health laboratory compared with direct immunofluorescence and cell culture in a medical center. J Clin Microbiol 41: 3597-3601, 2003.
9. Landry ML. Viral infections. In Burrows GN, Duffy TP and Copel J, Eds, Medical complications during pregnancy, 6th Edition, Elsevier, 2004.
10. Landry ML, Ferguson D, Cohen S, Peret TCT, Erdman DD. Detection of human metapneumovirus in clinical samples by immunofluorescence and shell vial centrifugation culture in three different cell lines. J Clin Microbiol 43:1950-1952, 2005.
11. Landry ML, Garner R, Ferguson D. Real-time nucleic acid sequence based amplification using molecular beacons for detection of enterovirus in clinical specimens. J Clin Microbiol 43:3136-3139, 2005.
12. Landry ML. Rapid Viral Diagnosis. In the Manual of Molecular and Clinical Laboratory Immunology, 7th Edition, American Society of Microbiology Press, Washington DC, 2006.
13. Campbell S and Landry ML. Rapid Antigen Tests. In Advanced Techniques in Diagnostic Microbiology, Kluwer Academic Publishers, 2006.
14. Kesebir D, Vazquez M, Weibel C, Shapiro E, Ferguson D, Landry ML, Kahn JS. Human bocavirus infection in young children in the United States: molecular epidemiology and clinical features associated with a newly emerging respiratory virus. J Infect Dis 194:1276-82, 2006.
15. Murray PR, Baron EJ, Jorgensen JH, Landry ML, and Pfaller MA. Eds, Manual of Clinical Microbiology, 9th Edition, American Society of Microbiology, Washington DC, 2007. (in press)