Carrie A. Redlich, MD, MPH Professor of Medicine Associate Director, Occupational and Environmental Medicine Program 135 College Street Room 383 Fax: 203-785-7391 Appointments: 203-785-4197 e-mail: carrie.redlich@yale.edu

Medical School

Yale University School of Medicine - MD, MPH

Residency

Yale University School of Medicine - Internal Medicine

Fellowship

University of Washington - Pulmonary and Critical Care Medicine
Yale University School of Medicine - Occupational and Environmental Medicine

Research Activities

Occupational lung diseases, isocyanate asthma, biomarker research.

Clinical Activities

Occupational and environmental lung diseases.

Selected Publications

• Liu Y, Stowe MH, Bello D, Woskie SR, Sparer J, Gore R, Youngs F, Cullen MR, Redlich CA. Respiratory Protection from isocyanate exposure in auto body shops: field performance of half facepiece organic vapor cartridge respirators. J of Occ Env Health. 2004. Submitted.

• Cartmel B, Dziura J, Cullen MR, Vegso S, Goodman G, Redlich CA. Cholesterol and triglyceride levels in the Vanguard population of the Carotene and Retinol Efficacy Trial (CARET), Ca Biomarkers & Prevention, in press.

• Wild DM, Redlich CA , Paltiel DA. A Model based cost-effectiveness analysis of screening for isocyanate-induced asthma. Occ Env Med, in press.

• Cullen MR, Barnett MJ, Balmes JR, Cartmel B, Redlich CA, Brodkin CA, Barnhart B, Rosenstock L, Goodman GE, Hammar SP, Thornquist MD, Omenn GS. Predictors of lung cancer among asbestos-exposed men in the b-carotene and retinol efficacy trial. Am J Epidem 2004, in press.

• Wisnewski AV, Liu Q, Liu J, Redlich CA. Glutathione protects human airway proteins and epithelial cells from isocyanates. Clinical and Experimental Allergy 2004, in press
  
• Sparer J, Stowe M, Bellow D, Liu Y, Gore R, Youngs F, Cullen MR, Redlich CA, Woskie SR. Isocyanate exposures in auto body shop work: the SPRAY study. J Occup Envir Hygiene 2004; 1:570-581

  Bello D, Woskie SR, Streicher RP, Liu Y, Stowe MH, Eisen EA, Ellenbecker MJ, Sparer J, Youngs F, Cullen MR, Redlich CA. 2004. Polyisocyanates in occupational environments: a critical review of exposures limits and metrics. Am J Ind Med 46:480-491.

• Wisnewski, AV, Cartier A, Stowe MH. Liu Q, Liu J, Redlich CA. 2004. Isocyanate vapor-induced antigenicity of human albumin, J Allergy Clin Immunol 113:1178-84.

• Pisani MA, Inouye SK, McNicoll L, Redlich CA. 2003. Screening for pre-existing cognitive impairment in older intensive care unit patients. J Am Geriatr Society 51:689-93.

• Pisani MA, Inouye SK, McNicoll L, Ely EW, Redlich CA. 2003. Under-recognition of preexisting cognitive impairment by physicians in older ICU. Chest 124:2267-74.

• Herrick, CA, Das J, Xu L, Wisnewski, AV, Redlich CA, Bottomly K. 2003. Differential roles for CD4 and CD8 T cells after diisocyanate sensitization: genetic control of TH2-induced lung inflammation. J Allergy Clin Immunol 111:1087-94.

• Wisnewski AV, Liu Q, Miller J-J, Magoski N and Redlich CA. 2002. Effects of diisocyanate exposure on human airway epithelial cells: In vitro cellular and molecular studies. Environ Health Perspect 110: 901-7.

• Redlich CA, and Karol MH. 2002. Diisocyanate Asthma: Clinical Aspects and Immunopathogenesis. International Immunopharmacology 2: 213-224.

• Redlich CA, Stowe MH, Coren BA, Wisnewski AV, Holm CT, Cullen MR. 2002. Diisocyanate-exposed auto body shop workers: A one-year follow-up. Am J Ind Med 42:511-518.

• Redlich CA, Wisnewski AV, Gordon T. 2002. Perspective: mouse models of diisocyanate asthma. Am J Respir Cell Mol Biol 27:385-390.
  

• Redlich CA, Stowe MH, Wisnewski AV, Eisen EA, Karol MH, Lemus R, Holm CT, Chung JS, Sparer J, Liu Y, Woskie SR, Appiah-Pippim J, Gore R, Cullen MR. 2001.Subclinical immunologic and physiologic responses in hexamethylene diisocyanate-exposed auto body shop workers.American Journal of Industrial Medicine 39:587-597.

• Wisnewski AV, Cain H, Redlich CA. Human gamma / delta T-cell lines derived from airway biopsies. Am J Resp Crit Care 2001; 24:332-8.

• Wisnewski AV, Srivastava R, Herrick C, Xu L, Lemus R, Cain H, Magoski N, Karol MK, Bottomly K, Redlich CA. 2000. Identification of human lung and skin proteins conjugated with diisocyanate in vitro and in vivo. Am J Resp Crit Care Med 162:2330-2336.

• Wisnewski AV, Lemus R, Karol MH, Redlich CA. 1999. Isocyanate-conjugated lung epithelial cell proteins: A link between exposure and asthma?ä  J All Clin Imm 104:341-7.

• Redlich CA, Cain H, Wisnewski AV. 1999. The immunology and prevention of isocyanate asthma: a model for low molecular weight asthma. Sem Resp Crit Care Med 20:591-599.