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As deputy dean, Leffell moves practice
into 21st century
Bottomly named deputy provost for
science, technology
NOTES
Notes

David Leffell

Kim Bottomly
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As deputy dean, Leffell moves practice into 21st
century
With his appointment as deputy dean for clinical affairs in February,
David J. Leffell, M.D., HS ’86, continues a task he began
almost 10 years ago, when he added a new portfolio to his work in the
clinic and laboratory. As associate dean for clinical affairs and director
of what was then called the Yale Faculty Practice, Leffell sought to improve
the business side of medicine. The faculty practice is now the Yale Medical
Group (YMG), where recent surveys show improved patient satisfaction,
as well as areas where improvement is needed. Most importantly, the YMG
has begun to introduce changes in the practice of medicine, helping it
move outside traditional departmental boundaries into interdisciplinary,
disease-based teams that include researchers as well as physicians.
“Because our knowledge of disease is so much more refined, we understand
that solutions to illness are not limited to a particular organ in which
the disease is expressed,” said Leffell, who will oversee the growth
and development of the clinical practice. Among his goals are strengthening
ties between clinical care and medical research and spreading the word
about Yale’s faculty expertise. He also hopes to improve the clinical
infrastructure by making it easier for patients to make appointments and
by ensuring close communications between referring physicians and specialists.

“To teach medical students to be doctors of the 21st century, to
take care of patients with new technology and medications of the 21st
century, you have to have a clinical practice of the 21st century,”
Leffell said.

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Bottomly
named deputy provost for science, technology
H. Kim Bottomly, Ph.D., has been named deputy provost for science,
technology and faculty development, effective July 1. Bottomly, who has
been at Yale since 1980, is professor of immunobiology, dermatology and
molecular, cellular and developmental biology. She also served as acting
chair of the Section of Immunobiology. Provost Andrew D. Hamilton, Ph.D.,
announced the appointment in April.
 As deputy provost, Bottomly will help shape and implement policies in
the natural sciences, anthropology, psychology, statistics and linguistics.
She will oversee Yale Engineering, the School of Forestry & Environmental
Studies, the Peabody Museum of Natural History, the Yale Institute for
Biospheric Studies and the Yale-affiliated Haskins Laboratories. Bottomly
will also work on initiatives to increase faculty diversity, improve recruitment
and retention of women and underrepresented minorities in science, and
enhance career development for faculty.


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Three Yale scientists have received
close to $1 million each from the Ellison Medical Foundation to pursue
research into infectious disease. The three are among the 10 Senior Scholars
in Global Infectious Disease announced in December.

Jorge E. Galán, Ph.D., D.V.M., the Lucille P. Markey Professor
of Microbiology and chair of the Section of Microbial Pathogenesis, will
study the bacterium Campylobacter jejuni, one of the most common causes
of gastrointestinal infection worldwide.

John R. Carlson, Ph.D., the Eugene Higgins Professor of Molecular,
Cellular and Developmental Biology, will explore new approaches to the
design of repellents and traps for disease-carrying insects.

Ruslan Medzhitov, Ph.D., professor of immunobiology and a Howard Hughes
Medical Institute investigator, will examine how immune system responses
to one infectious agent affect the body’s defenses against concurrent
infections.

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Thomas Gill
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Thomas M. Gill, M.D., FW ’94,
associate professor of medicine (geriatrics), and Michael Cappello,
M.D., FW ’95, associate professor of pediatrics and epidemiology,
have been elected to the American Society for Clinical Investigation (ASCI),
one of the nation’s oldest and most respected medical honor societies.
The ASCI membership includes physician-scientists elected for their achievements
in biomedical research.
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Steven Hebert


Stefan Somlo


Walter F. Boron

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Two Yale physician-scientists were honored
with major awards in the field of kidney research at the World Congress
of Nephrology meeting in Singapore in June.

Steven C. Hebert, M.D., the chair and C.N.H. Long Professor of
Cellular and Molecular Physiology and professor of medicine, and Stefan
Somlo, M.D., FW ’91, the C.N.H. Long Professor of Medicine and
chief of the Section of Nephrology, are being recognized for important
discoveries.

Hebert will receive the A.N. Richards Award, which carries a $10,000 cash
prize, from the International Society of Nephrology (ISN) for three discoveries
in the field of ion transport and ion sensing. Somlo will share the Lillian
Jean Kaplan International Prize for Advancement in the Understanding of
Polycystic Kidney Disease for his work in discovering genes that cause
polycystic kidney and liver diseases. Somlo and co-recipient Gregory G.
Germino, M.D., HS ’87, of the Johns Hopkins School of Medicine will
receive $50,000 each from The PKD Foundation and the ISN.

A third Yale nephrologist, Walter F. Boron, M.D., Ph.D., professor
of cellular and molecular physiology, has been selected to receive the
Homer W. Smith Award, the American Society of Nephrology’s top honor
for basic research. The award, which carries a $10,000 cash prize, will
be presented at the society’s annual meeting in November in Philadelphia.
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Two Yale psychiatrists received the American
Psychiatric Association’s APIRE/Kempf Fund Award for Research Development
in Psychobiological Psychiatry at the association’s annual meeting
in Atlanta in May.

John H. Krystal, M.D. ’84, the Robert L. McNeil Jr. Professor
of Clinical Pharmacology and deputy chair for research in the Department
of Psychiatry, and Daniel H. Mathalon, M.D., Ph.D., assistant professor
of psychiatry, were recognized for providing new insights into the neurobiology
and treatment of cognitive impairments associated with schizophrenia.
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In March Sidney J. Blatt, Ph.D., professor of
psychiatry and psychology and chief of psychology in the Department of
Psychiatry, in collaboration with colleagues in Belgium, published a book,
The Theory and Treatment of Depression: Towards a Dynamic Interactionism
Model, that grew out of a collaboration begun in 2003. Blatt spent
a month that year at the Catholic University of Leuven as a visiting professor.
A colleague at Yale, Paul L. Errera, M.D., HS ’57, professor
emeritus of psychiatry and a native of Belgium, sent greetings via videotape.
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Hal Blumenfeld |
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Hal Blumenfeld, M.D., Ph.D., FW ’98, assistant
professor of neurology, neurobiology and neurosurgery, has received the
Dreifuss-Penry Epilepsy Award from the American Academy of Neurology.
The award recognizes physicians in the early stages of their careers who
have contributed to epilepsy research.
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Ronald Breaker |
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Ronald R. Breaker, Ph.D., associate professor
of molecular, cellular and developmental biology, has been named a Howard
Hughes Medical Institute investigator and the Henry Ford II Professor
of Molecular, Cellular and Developmental Biology. Breaker’s lab
explores the “RNA world,” the idea that the Earth’s
first life forms were composed of RNA rather than DNA. His studies have
led him to discover dozens of regulatory structures, known as riboswitches,
which might be used to control the activity of genes inserted into cells
during the course of gene therapy.
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David C. Cone, M.D., associate professor of surgery
(emergency medicine) and public health, was installed as president-elect
of the National Association of EMS Physicians at the group’s annual
meeting in January.
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Linda Degutis |
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Linda C. Degutis, M.S.N. ’82, Dr.Ph. ’94,
associate professor of surgery (emergency medicine) and epidemiology and
public health, was elected chair of the executive board of the American
Public Health Association, the primary association for public health professionals.
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Vincent DeVita Jr. |
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Vincent T. DeVita Jr., M.D., HS ’66, the
Amy and Joseph Perella Professor of Medicine, has been named editor in
chief of a new journal for oncologists, Nature Clinical Practice Oncology.
DeVita previously served as head of the Yale Cancer Center and director
of the National Cancer Institute.
Marie L. Landry, M.D., HS ’77, FW ’81,
professor of laboratory medicine and director of the Clinical Virology
Laboratory at Yale-New Haven Hospital, received the 2005 Diagnostic Virology
Award from the Pan American Society for Clinical Virology in May for outstanding
contributions to the field.
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Robert J. Levine, M.D., HS ’63, professor
of medicine and co-chair of the Yale Bioethics Project, has received the
Health Improvement Institute’s Lifetime Achievement Award for Excellence
in Human Research Protection. Levine has contributed to the literature
of the field of protection of human research subjects by publishing over
200 articles and one major monograph and by founding and editing IRB:
A Review of Human Subjects Research.
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John MacMicking |
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John D. MacMicking, Ph.D., assistant professor
in the Section of Microbial Pathogenesis, has been selected as a 2005
Searle Scholar as part of a program that supports the independent research
of young faculty in the biomedical sciences and chemistry. In 2004 MacMicking
also received the Mallinckrodt Foundation Program Scholar Award, given
annually to young scientists starting their careers. He studies host innate
immunity, with an emphasis on the role played by interferon pathways against
intracellular infections like tuberculosis.
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Bruce McClennan |
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Bruce L. McClennan, M.D., professor and chair
of diagnostic radiology, was elected president of the American Roentgen
Ray Society, effective May 15. The oldest radiology society in the United
States, it has advanced radiology through annual scientific and educational
meetings and the American Journal of Roentgenology.
Stephanie S. O’Malley, Ph.D., professor of psychiatry and director of the department’s Division of Substance Abuse Research, has received the 2004 Dan Anderson Research Award. The award, sponsored by the Butler Center for Research at the Hazelden Foundation, honors researchers who have advanced the study of addiction recovery.
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Anna Marie Pyle |
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Anna Marie Pyle, Ph.D., has been appointed the
William Edward Gilbert Professor of Molecular Biophysics and Biochemistry.
Her research explores how RNA folds and organizes itself to catalyze reactions.
Since 2002, Pyle has also been a Howard Hughes Medical Institute investigator.

The Bayer Pharmaceuticals Corp. has given the 2004 Bayer Award to Raymond R. Russell, M.D., Ph.D., FW ’00, assistant professor of medicine (cardiology). Russell studies cardiac function and metabolism and the changes associated with disease states. |
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Robert Udelsman |
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Robert Udelsman, M.D., M.B.A., the Lampman Professor
of Surgery and Oncology and chair of surgery, was elected president of
the American Association of Endocrine Surgeons. Membership includes surgeons
who devote significant portions of their practice or research to endocrine
surgery and who are certified by the American Board of Surgery.
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Stephen Waxman |
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Stephen G. Waxman, Ph.D., M.D., professor and
chair of neurology and professor of pharmacology and neurobiology, has
been named the Bridget Marie Flaherty Professor of Molecular Neurology.
Waxman, a renowned neurologist and molecular neuroscientist, studies the
roles of sodium channels in multiple sclerosis, spinal cord injury and
neuropathic pain.
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